| Объем | 100 мкл |
| Синонимы | Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3, MBD3, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O95983 |
| Иммуноген | Synthesized peptide derived from C-terminal of human MBD3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (). Recruits histone deacetylases and DNA methyltransferases.<br/><br/>Hendrich B., Mol. Cell. Biol. 18:6538-6547(1998).<br/>Grimwood J., Nature 428:529-535(2004).<br/>Tatematsu K., Genes Cells 5:677-688(2000). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using MBD3 antibody.
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Наименование: MBD3 Antibody.