| Объем | 50 мкг |
| Синонимы | Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3), MBD3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O95983 |
| Иммуноген | Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
| Примечание | Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Methyl-CpG-binding domain protein 3 |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Jurkat whole cell lysate, HEK293 whole cell lysate, Mouse brain tissue
All lanes: MBD3 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 33, 30 kDa
Observed band size: 33 kDa
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Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013532LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA013532LA01HU at dilution of 1:100
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Наименование: MBD3 Antibody.