MMP14 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | MT1-MMP, MATRIX METALLOPROTEINASE 14, MEMBRANE-TYPE, MEMBRANE-TYPE MATRIX METALLOPROTEINASE 1, matrix metalloproteinase 14 (membrane-inserted). | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P50281 | | Иммуноген | Synthesized peptide derived from human MMP-14. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.<br/><br/>Bimal K. Ray, Circ. Res., Nov 2004, 95: 1082 - 1090. <br/>Sharon Elliot, Invest. Ophthalmol. Vis. Sci., Apr 2006, 47: 1696 - 1702. <br/>Hongqing Q. Ye, Invest. Ophthalmol. Vis. Sci., Sep 2000, 41: 2894. <br/>Leanne J. Bakke, Biol Reprod, Jun 2002, 66: 1627. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from NIH/3T3 cells, using MMP-14 antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MMP-14 antibody.
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Наименование: MMP14 Antibody.