| Объем | 100 мкг |
| Синонимы | Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1), MICU2, EFHA1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8IYU8 |
| Иммуноген | Recombinant Human Calcium uptake protein 2, mitochondrial protein (26-247AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
| Примечание | Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Calcium uptake protein 2, mitochondrial |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA818265LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA818265LA01HU at dilution of 1:100
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Наименование: MICU2 Antibody.