MCM5 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CDC46, DNA replication licensing factor MCM5, minichromosome maintenance deficient protein 5, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P33992 | | Иммуноген | Synthesized peptide derived from human MCM5 antibody. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity By similarity. Interacts with MCMBP.<br/><br/>Robert A. Sclafani, Genetics, May 2002, 161: 47. <br/>Marylynn Snyder, PNAS, Oct 2005, 102: 14539 - 14544. <br/>Christopher J. DaFonseca, PNAS, Mar 2001, 98: 3034. <br/>Cathleen M. Lake, Genetics, Jun 2007, 10.1534 <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human tonsil tissue using MCM5 antibody.
 | Immunofluorescence analysis of HepG2 cells, using MCM5 antibody.
 | Western blot analysis of extracts from HepG2 cells, using MCM5 antibody.
 | Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and cells (Lane 4), using MCM5 antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: MCM5 Antibody.