| Объем | 100 мкл |
| Синонимы | MAP/microtubule affinity-regulating kinase 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9P0L2 |
| Иммуноген | Synthetic peptide of human MARK1 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Примечание | The microtubule matrix within a cell plays a central role in intracellular transport, cell shape during differentiation and chromosome partitioning during mitosis. During these processes, microtubules transition rapidly between stable and dynamic states. MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA259165(MARK1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA259165(MARK1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: MARK1 Antibody.