MAP3K13 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Mitogen-activated protein kinase kinase kinase 13, EC 2.7.11.25, Mixed lineage kinase, MLK, Leucine zipper-bearing kinase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O43283 | | Иммуноген | Synthesized peptide derived from internal of human M3K13. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.<br/><br/>Sakuma H., J. Biol. Chem. 272:28622-28629(1997).<br/>Schultz S.J., Cell Growth Differ. 4:821-830(1993).<br/>Ikeda A., FEBS Lett. 488:190-195(2001).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, HUVEC cells and HepG2 cells, using M3K13 antibody.
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Наименование: MAP3K13 Antibody.