| Объем | 50 мкг |
| Синонимы | Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9HBX8 |
| Иммуноген | Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
| Примечание | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Leucine-rich repeat-containing G-protein coupled receptor 6 |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: U87 whole cell lysate
All lanes: LGR6 antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 105, 90, 100 kDa
Observed band size: 105 kDa
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Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA884515LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA884515LA01HU at dilution of 1:100
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Наименование: LGR6 Antibody.