Loxl2 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2), Loxl2
Клональность	Polyclonal Antibody
Организм	Mouse
uniprot	P58022
Иммуноген	Recombinant Mouse Lysyl oxidase homolog 2 protein (26-776AA)
Источник	Rabbit
Видовая специфичность	Mouse
Применение	ELISA
Примечание	Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 By similarity. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Cancer, Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA013041LD01MO
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Loxl2 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).