| Объем | 100 мкг |
| Code NO# | 2C12F3 |
| Синонимы | MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein |
| Тип антител | Monoclonal Antibody |
| Видовая специфичность | Human |
| Uniport ID | P52701 |
| Иммуноген | Recombinant Human MSH6 Protein |
| Источник | mouse |
| Видовая специфичность 1 | Human |
| Перекрестная реактивность | specific for human Msh6 denatured and native forms. |
| Применение | ELISA,IHC,Recommended dilution:IHC:1:50-1:500 |
| Примечание | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed. |
| Метод очистки | >95%,Protein G purified |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Станица на сайте производителя | ссылка |
Immunohistochemical of paraffin-embedded Human lung cancer tissue using CSB-MA0150321A0m at dilution of 1:200.
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Наименование: MSH6 Monoclonal Antibody.