| Объем | 100 мкл |
| Синонимы | Myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P58340 |
| Иммуноген | Synthesized peptide derived from internal of human MLF1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.<br/><br/>Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204].<br/>Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101].<br/>Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cardiovascular,Cell biology,Tags & Cell Markers,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells, using MLF1 antibody.
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Наименование: MLF1 Antibody.