MKL1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Myocardin-related transcription factor A, MRTF-A, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q969V6 | | Иммуноген | Synthesized peptide derived from N-terminal of human MKL1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases, its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.<br/><br/>Ma Z., Nat. Genet. 28:220-221(2001).<br/>Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).<br/>Nagase T., DNA Res. 7:65-73(2000).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Metabolism,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells and HUVEC cells, using MKL1 antibody.
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