ICAM1 (Ab-512) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ICA1, ICAM1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P05362 | | Иммуноген | Peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. <br /><br />Greenwood J, et al. (2003) J Immunol, 171(4):2099-2108. <br />Zhou Z, et al. (2005) Eur J Pharmacol, 513(1-2):1-8. <br />Chen YH, et al. (2001) J Cell Biochem, 82(3):512-521 <br /> ,</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Cardiovascular,Immunology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from MDA cells using ICAM-1(Ab-512) Antibody.
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