| Объем | 100 мкл |
| Синонимы | Methylated-DNA--protein-cysteine methyltransferase, EC 2.1.1.63, 6-O-methylguanine-DNA methyltransferase, MGMT, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P16455 |
| Иммуноген | Synthesized peptide derived from internal of human MGMT. |
| Источник | Rabbit |
| Видовая специфичность | Human, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.<br/><br/>Tano K., Proc. Natl. Acad. Sci. U.S.A. 87:686-690(1990).<br/>Rydberg B., J. Biol. Chem. 265:9563-9569(1990).<br/>Koike G., J. Biol. Chem. 265:14754-14762(1990) |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using MGMT antibody.
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Наименование: MGMT Antibody.