ITGA6 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain, Integrin alpha-6 light chain, Processed integrin alpha-6 (Alpha6p)], ITGA6 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P23229 | | Иммуноген | Recombinant Human Integrin alpha-6 protein (625-866AA) | | Источник | Rabbit | | Видовая специфичность | Human, Rat, Mouse | | Применение | ELISA, WB, IF, Recommended dilution: WB:1:500-1:5000, IF:1:200-1:500 | | Примечание | Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Integrin alpha-6 | | Области исследований | Developmental biology, Signal transduction, Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western Blot
Positive WB detected in: Rat heart tissue, Rat kidney tissue, Mouse heart tisseu, Mouse kidney tissue
All lanes: ITGA6 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 127, 120, 123, 122, 125, 107 kDa
Observed band size: 100 kDa
 | Immunofluorescence staining of Hela cells with CSB-PA011869LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Наименование: ITGA6 Antibody.