HSD17B10 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ABAD, CAMR, HCD2, MHBD, HADH2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q99714 | | Иммуноген | Peptide sequence around aa.253~257(L-D-G-A-I)derived from Human ERAB. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). <br/><br/>Holzmann J., Frank P., Loeffler E., Bennett K.L., Gerner C., Rossmanith W. Cell 135:462-474(2008) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Tags & Cell Markers,Metabolism | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from JK, HUVEC, HepG2 and Hela cells using ERAB Antibody
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