MBTPS2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Membrane-bound transcription factor site-2 protease, EC 3.4.24.85, S2P endopeptidase, Site-2 protease, Sterol regulatory element-binding proteins intramembrane protease | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O43462 | | Иммуноген | Synthesized peptide derived from internal of human MBTPS2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IF,IF:1:100-1:500 | | Примечание | Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.<br/><br/>Rawson R.B., Mol. Cell 1:47-57(1997).<br/>Ye J., Proc. Natl. Acad. Sci. U.S.A. 97:5123-5128(2000).<br/> <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cardiovascular,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence analysis of A549 cells, using MBTPS2 antibody.
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