| Объем | 100 мкл |
| Синонимы | EC 2.7.11.1, HPK/GCK-like kinase HGK, M4K4, MAP4K4, MAPK/ERK kinase kinase kinase 4 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O95819 |
| Иммуноген | Synthesized peptide derived from internal of human MEKKK 4. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.<br/><br/>Yao Z., J. Biol. Chem. 274:2118-2125(1999).<br/>Wright J.H., Mol. Cell. Biol. 23:2068-2082(2003).<br/>Ishikawa K., DNA Res. 5:169-176(1998). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO cells and HUVEC cells, using MEKKK 4 antibody.
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Immunofluorescence analysis of A549 cells, using MEKKK 4 antibody.
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Наименование: MAP4K4 Antibody.