| Объем | 100 мкл |
| Синонимы | MAGED1 |
| Клональность | Polyclonal Antibody |
| Организм | Mouse |
| uniprot | Q9QYH6 |
| Иммуноген | Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1. |
| Источник | Rabbit |
| Видовая специфичность | Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.<br/><br/>Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20.<br/>Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31.<br/>Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from PC12 cells using Melanoma-associated antigen D1 Antibody and the same antibody preincubated with blocking peptide.
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Наименование: Maged1 Antibody.