| Объем | 100 мкг |
| Синонимы | Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1), HSPA8, HSC70 HSP73 HSPA10 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P11142 |
| Иммуноген | Recombinant Human Heat shock cognate 71 kDa protein (418-597AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Heat shock cognate 71 kDa protein |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: HEK293 whole cell lysate, A549 whole cell lysate, Colo320 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue, Rat brain tissue, Rat lung tissue
All lanes: HSPA8 antibody at 3.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71, 54 kDa
Observed band size: 71 kDa
 |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA03249A0Rb at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA03249A0Rb at dilution of 1:100
 |
Western Blot
Positive WB detected in: 293 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, A549 whole cell lysate
All lanes: HSPA8 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71, 54 kDa
Observed band size: 71 kDa
 |
| | |
Наименование: HSPA8 Antibody.