| Объем | 100 мкл |
| Синонимы | HNRNPC, HNRPC, Heterogeneous nuclear ribonucleoproteins C1/C2, ROC, hnRNP C1 / hnRNP C2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P07910 |
| Иммуноген | Synthesized peptide derived from internal of human hnRNP C1/C2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.<br/><br/>Burd C.G., Proc. Natl. Acad. Sci. U.S.A. 86:9788-9792(1989).<br/>Swanson M.S., Mol. Cell. Biol. 7:1731-1739(1987).<br/>Merrill B.M., Nucleic Acids Res. 17:8441-8449(1989).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells and COLO205 cells, using hnRNP C1/C2 antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using hnRNP C1/C2 antibody.
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Immunofluorescence analysis of HUVEC cells, using hnRNP C1/C2 antibody.
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Наименование: HNRNPC Antibody.