| Объем | 100 мкл |
| Синонимы | Laminin subunit beta-1 [Precursor], Laminin B1 chain, LAMB1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P07942 |
| Иммуноген | Synthesized peptide derived from C-terminal of human LAMB1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.<br/><br/>Vuolteenaho R., J. Biol. Chem. 265:15611-15616(1990).<br/>Pikkarainen T., J. Biol. Chem. 262:10454-10462(1987).<br/>Scherer S.W., Science 300:767-772(2003).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cardiovascular,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using LAMB1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using LAMB1 antibody.
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Immunofluorescence analysis of HeLa cells, using LAMB1 antibody.
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Наименование: LAMB1 Antibody.