GRIA2 (Ab-880) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | GRIA2, GluR-2, GluR-B, GluR-K2, AMPA 2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P42262 | | Иммуноген | Peptide sequence around aa.878~882 (I-E-S-V-K) derived from Human Glutamate receptor 2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. <br /><br />Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. <br />Hanley JG, et al. (2002) Neuron. 34(1): 53-67</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from mouse brain and rat brain tissue using GluR2 (Ab-880) antibody.
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