| Объем | 100 мкл |
| Синонимы | Insulin-like growth factor I receptor |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P08069 |
| Иммуноген | Peptide sequence around aa. 1278~1282 (S-F-Y-Y-S ) derived from Human IGF-1R . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
| Примечание | This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.<br/><br/>Adams, T.E. et al. (2000) Cell. Mol. Life Sci. 57, 1050-1093<br/>Baserga, R. et al. (2000) Oncogene 19, 5574-5581<br/>Scheidegger, K.J. et al. (2000) J. Biol. Chem. 275, 38921-38928.<br/>O'Connor R, et al. Mol Cell Biol 1997 Jan, 17(1): 427-35<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cancer,Developmental biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293,3T3 and Hela cells using IGF-1R(Ab-1280) Antibody.
 |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R(Ab-1280) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 |
| | |
Наименование: IGF1R (Ab-1280) Antibody.