FES AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Proto-oncogene tyrosine-protein kinase Fes/Fps, EC 2.7.10.2, C-Fes, FES, FPS | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P07332 | | Иммуноген | Synthesized peptide derived from internal of human FES. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.<br/><br/>Alcalay M., Oncogene 5:267-275(1990).<br/>Roebroek A.J.M., EMBO J. 4:2897-2903(1985).<br/>Scott A., J. Biomol. NMR 31:357-361(2005).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HUVEC cells, treated with serum (20%, 30mins), using FES antibody.
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Наименование: FES Antibody.