| Объем | 100 мкл |
| Синонимы | Tumor necrosis factor ligand superfamily member 6, Fas antigen ligand, Fas ligand, CD178 antigen, CD95L protein |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P48023 |
| Иммуноген | Synthesized peptide derived from internal of human FAS ligand. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.<br/><br/>Alderson M., J. Exp. Med. 181:71-77(1995).<br/>Takahashi T., Int. Immunol. 6:1567-1574(1994).<br/>Gregory S.G., ure 441:315-321(2006).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology,Immunology,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using FAS ligand antibody.
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Western blot analysis of extracts from 293 cellls, using FAS ligand antibody.
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Western blot analysis of extracts from 3T3 cells (Lane 2), using FAS ligand antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: FASLG Antibody.