| Объем | 50 мкг |
| Синонимы | Low affinity immunoglobulin gamma Fc region receptor II-b (IgG Fc receptor II-b) (CDw32) (Fc-gamma RII-b) (Fc-gamma-RIIb) (FcRII-b) (CD antigen CD32), FCGR2B, CD32 FCG2 IGFR2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P31994 |
| Иммуноген | Recombinant Human Low affinity immunoglobulin gamma Fc region receptor II-b protein (12-289AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Low affinity immunoglobulin gamma Fc region receptor II-b |
| Области исследований | Immunology, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: FCGR2B antibody at 2 µg/ml + Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 35, 32, 34 kDa
Observed band size: 35, 50 kDa
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Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA10839A0Rb at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA10839A0Rb at dilution of 1:100
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Immunofluorescent analysis of HepG2 cells using CSB-PA10839A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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