| Объем | 100 мкл |
| Синонимы | FADD, Fas (TNFRSF6)-associated via death domain, FAS-associated death domain protein, FAS-associating death domain-containing protein, Fas-associating protein with death domain |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q61160/Q13158 |
| Иммуноген | Synthesized peptide derived from C-terminal of human FADD. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis By similarity. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling By similarity.<br/><br/>Zhang J., Mol. Cell. Biol. 16:2756-2763(1996).<br/>Hsu H., Cell 84:299-308(1996).<br/>Carninci P., Science 309:1559-1563(2005)<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from A549 cells (Lane 2), using FADD (Ab-191) antiobdy. The lane on the left is treated with synthesized peptide.
 |
| | |
Наименование: FADD (Ab-191) Antibody.