| Объем | 100 мкг |
| Синонимы | Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (Exonuclease 3'-5' domain-like-containing protein 2), EXD2, C14orf114 EXDL2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NVH0 |
| Иммуноген | Recombinant Human Exonuclease 3'-5' domain-containing protein 2 protein (137-245AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200 |
| Примечание | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Exonuclease 3'-5' domain-containing protein 2 |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Mouse brain tissue, Mouse stomach tissue
All lanes: EXD2 antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71, 57 kDa
Observed band size: 71 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA873662LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA873662LA01HU at dilution of 1:100
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Наименование: EXD2 Antibody.