GZMB AntibodyСпецификация| Объем | 100 мкл | | Синонимы | 3.4.21.79, CCPI, CGL-1, CGL1, CSP-B | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P10144 | | Иммуноген | Synthesized peptide derived from human Granzyme B. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.<br/><br/>David A. Jans, J. Biol. Chem., Nov 1996, 271: 30781.<br/>Eugene Estella, Diabetes, Aug 2006, 55: 2212 - 2219.<br/>Yong Gu, J. Biol. Chem., May 1996, 271: 10816.<br/>Jiuru Sun, J. Biol. Chem., Nov 1996, 271: 27802.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cell biology,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from NIH/3T3 cells, using Granzyme B antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Granzyme B antibody.
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Наименование: GZMB Antibody.