Grin2b AntibodyСпецификация| Объем | 100 мкл | | Синонимы | NMDAR2B, NR2B, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q00960 | | Иммуноген | Peptide sequence around aa.1250-1254(N-L-Y-D-I) derived from Human NMDANR2B Subunit. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death<br/><br/>Kornau H.C., Schenker L.T., Kennedy M.B., Seeburg P.H.Science 269:1737-1740(1995) <br/>Kurschner C., Mermelstein P.G., Holden W.T., Surmeier D.J.Mol. Cell. Neurosci. 11:161-172(1998) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from T98G cells using NMDANR2B Subunit Antibody
 | | | |
Информация для заказа |
Наименование: Grin2b Antibody.