ERAP1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | A- LAP, APPILS, ARTS-1, Adipocyte-derived leucine aminopeptidase precursor, Aminopeptidase PILS | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9NZ08 | | Иммуноген | Synthesized peptide derived from internal of human ARTS-1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.<br/><br/>Hattori A., J. Biochem. 130:235-241(2001).<br/>Nakajima D., DNA Res. 9:99-106(2002).<br/>Clark H.F., Genome Res. 13:2265-2270(2003).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cardiovascular,Cell biology,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells, Jurkat cells and HUVEC cells, using ARTS-1 antibody.
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Наименование: ERAP1 Antibody.