| Объем | 100 мкл |
| Синонимы | Growth arrest and DNA-damage-inducible proteins-interacting protein 1, CR6-interacting factor 1, CRIF1, CKII beta-associating protein, Papillomavirus L2-interacting nuclear protein 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8TAE8 |
| Иммуноген | Synthesized peptide derived from internal of human GADD45GIP1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.<br/><br/>Goernemann J., Virology 303:69-78(2002).<br/>Chung H.K., J. Biol. Chem. 278:28079-28088(2003).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human brain tissue using GADD45GIP1 antibody.
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Наименование: GADD45GIP1 Antibody.