| Объем | 100 мкл |
| Синонимы | 180 kDa protein downstream of CRK, dedicator of cytokinesis protein 1, DOC1, DOCK180, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q14185 |
| Иммуноген | Synthesized peptide derived from internal of human DOCK1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.<br/><br/>Hasegawa H., Mol. Cell. Biol. 16:1770-1776(1996).<br/>Deloukas P., Nature 429:375-381(2004).<br/>Matsuda M., J. Biol. Chem. 271:14468-14472(1996).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, using DOCK1 antibody.
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Наименование: DOCK1 Antibody.