DKK3 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (hDkk-3), DKK3, REIC | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9UBP4 | | Иммуноген | Recombinant Human Dickkopf-related protein 3 protein (22-350AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Области исследований | Signal transduction, Stem cells | | Ссылка на страницу на сайте производителя | ссылка | | | |
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Наименование: DKK3 Antibody.