| Объем | 100 мкл |
| Синонимы | Protein DBF4 homolog A, Activator of S phase kinase, DBF4-type zinc finger-containing protein 1, Chiffon homolog A, DBF4 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UBU7 |
| Иммуноген | Synthesized peptide derived from N-terminal of human DBF4. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.<br/><br/>Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999).<br/>Jiang W., EMBO J. 18:5703-5713(1999).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from NIH-3T3 cells treated with H2O2 (100uM, 30mins) and COS-7 cells treated with PMA (125mg/ml, 30mins), using DBF4 antibody.
 |
| | |
Наименование: DBF4 Antibody.