| Объем | 100 мкл |
| Синонимы | Cytochrome P450 2A6, EC 1.14.14.1, CYPIIA6, Coumarin 7-hydroxylase, P450 IIA3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P11509 |
| Иммуноген | Synthesized peptide derived from N-terminal of human Cytochrome P450 2A6. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.<br/><br/>Miles J.S., ic Acids Res. 17:2907-2917(1989).<br/>Yamano S., Biochemistry 29:1322-1329(1990).<br/>Saito S., J. Hum. Genet. 48:249-270(2003).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 2A6 antibody.
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