ETHE1 Antibody, FITC conjugated

Спецификация

Объем	100 мкг
Синонимы	Persulfide dioxygenase ETHE1, mitochondrial (EC 1.13.11.18) (Ethylmalonic encephalopathy protein 1) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1), ETHE1, HSCO
Клональность	Polyclonal Antibody
Организм	Human
uniprot	O95571
Иммуноген	Recombinant Human Persulfide dioxygenase ETHE1, mitochondrial protein (8-254AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	FITC
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Cancer, Cell biology, Metabolism, Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA007847HC01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: ETHE1 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке).