CREBBP AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CREB-binding protein, CBP CBP/MOZ FUSION GENE, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q92793 | | Иммуноген | Synthesized peptide derived from human CREB-BP. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.<br/><br/>Zoi Lygerou, Nucleic Acids Res., Feb 1994, 22: 5332 - 5340.<br/>Karsten Grote, J. Biol. Chem., Dec 2004, 279: 55675 - 55681.<br/>Kumi Nagamoto-Combs, J. Biol. Chem., Feb 1997, 272: 6051.<br/>Stephen J. Elliman, Isaac, J. Biol. Chem., Jan 2006, 281: 16 -19 <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism,Microbiology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, treated with insulin (0.01U/ml, 15mins), using CREB-BP antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB-BP antibody.
 | Immunofluorescence analysis of A549 cells, using CREB-BP antibody.
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Наименование: CREBBP Antibody.