| Объем | 100 мкл |
| Синонимы | chloride intracellular channel 4 (mitochondrial), D0Jmb3, mc3s5, mtCLIC, TU-74 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y696 |
| Иммуноген | Synthesized peptide derived from N-terminal of human CLIC4. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).<br/><br/>Wiemann S., Genome Res. 11:422-435(2001).<br/>Edwards J.C., Am. J. Physiol. 276:F398-F408(1999).<br/>Chuang J.Z., J. Neurosci. 19:2919-2928(1999). <br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT-29 cells, using CLIC4 antibody.
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Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using CLIC4 antibody.
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Наименование: CLIC4 Antibody.