CLDN10 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Claudin-10, OSP-like protein, CLDN10, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P78369 | | Иммуноген | Synthesized peptide derived from human Claudin 10. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores, isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney.<br/><br/>Siu Tim Cheung, Clin. Cancer Res., Jan 2005, 11: 551 - 556.<br/>Hiroki Fujita, J. Histochem. Cytochem., Aug 2006, 54: 933 - 944.<br/>Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006, 291: F1288 - F1299.<br/>Anne Florin, Endocrinology, Mar 2005, 146: 153 | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from LOVO cells, using Claudin 10 antibody.
 | Western blot analysis of extracts from A549 cells (Lane 2), using Claudin 10 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: CLDN10 Antibody.