| Объем | 100 мкг |
| Синонимы | A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4) (EC 3.4.24.82) (ADMP-1) (Aggrecanase-1), ADAMTS4, KIAA0688 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O75173 |
| Иммуноген | Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 4 protein (213-319AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
| Примечание | Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Cancer, Cell biology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: ADAMTS4 antibody at 6µg/ml + Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 90 kDa
Observed band size: 90 kDa
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Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA001311LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA001311LA01HU at dilution of 1:100
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Western Blot
Positive WB detected in: mouse kidney tissue
All lanes: ADAMTS4 antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 91 kDa
Observed band size: 91 kDa
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001311LA01HU at dilution of 1:100
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IHC image of CSB-PA001311LA01HU diluted at 1:250 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized tissue using an HRP conjugated SP system.
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Наименование: ADAMTS4 Antibody.