| Объем | 100 мкл |
| Синонимы | Homeobox protein DLX-5, DLX5, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P56178 |
| Иммуноген | Synthesized peptide derived from internal of human DLX5. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Hillier L.W., Nature 424:157-164(2003).<br/>Willis D.M., J. Biol. Chem. 277:37280-37291(2002).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, 293 cells and COLO205 cells, using DLX5 antibody.
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using DLX5 antibody.
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Наименование: DLX5 Antibody.