DLC1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Rho-type GTPase-activating protein 7, Deleted in liver cancer 1 protein, Dlc-1, HP protein, StAR-related lipid transfer protein 12 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q96QB1 | | Иммуноген | Synthesized peptide derived from internal of human RHG07. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.<br/><br/>Yuan B.Z., Cancer Res. 58:2196-2199(1998).<br/>Nagase T., DNA Res. 7:347-355(2000).<br/>Wilson P.J., Hum. Mutat. 15:156-165(2000).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Tags & Cell Markers,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using RHG07 antibody.
 | Immunofluorescence analysis of A549 cells, using RHG07 antibody.
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Наименование: DLC1 Antibody.