| Объем | 50 мкл |
| Синонимы | Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form], DKK4 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UBT3 |
| Иммуноген | Recombinant Human Dickkopf-related protein 4 protein (19-224AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Dickkopf-related protein 4 antibody at 8µg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25 kDa
Observed band size: 25 kDa
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA883367ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA883367ESR2HU at dilution of 1:100
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Наименование: DKK4 Antibody.