| Объем | 100 мкл |
| Синонимы | ACVL1, ACVRL1, ACVRLK1, ALK-1, Activin receptor-like kinase 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P37023 |
| Иммуноген | Synthesized peptide derived from internal of human ACVL1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.<br/><br/>ten Dijke P., Oncogene 8:2879-2887(1993).<br/>Attisano L., Cell 75:671-680(1993).<br/>Berg J.N., Am. J. Hum. Genet. 61:60-67(1997). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ACVL1 antibody.
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Immunofluorescence analysis of HeLa cells, using ACVL1 antibody.
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Western blot analysis of extracts from K562 cells, using ACVL1 antibody.
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Western blot analysis of extracts from 3T3 cells (Lane 2), using ACVL1 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: ACVRL1 Antibody.