| Объем | 100 мкл |
| Синонимы | CLAP1, MAST1, Multiple asters 1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q7Z460 |
| Иммуноген | Synthesized peptide derived from internal of human CLASP1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.<br/><br/>Maiato H., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.<br/>Hillier L.W., Nature 434:724-731(2005).<br/>Akhmanova A., Cell 104:923-935(2001).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using CLASP1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CLASP1 antibody.
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Наименование: CLASP1 Antibody.