DCX AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DCX, DC, DBCN | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O43602 | | Иммуноген | Peptide sequence around aa.413~417( P-T-S-P-G) derived from Human Doublecortin. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.<br/><br/>Des Portes V., Pinard J.-M., Billuart P. Chelly J.Cell 92:51-61(1998)<br/>Pilz D.T., Matsumoto N., Minnerath S.R., Mills P. Hum. Mol. Genet. 7:2029-2037(1998) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Tags & Cell Markers | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from Molt-4 and Hela cells using Doublecortin Antibody
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Наименование: DCX Antibody.