CYR61 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | Protein CYR61 (CCN family member 1) (Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding protein 10) (IBP-10) (IGF-binding protein 10) (IGFBP-10) (Protein GIG1), CYR61, CCN1 GIG1 IGFBP10 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O00622 | | Иммуноген | Recombinant Human Protein CYR61 protein (25-381AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 | | Примечание | Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Protein CYR61 | | Области исследований | Cancer, Cardiovascular, Immunology, Signal transduction, Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA10349A0Rb at dilution of 1:100
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Наименование: CYR61 Antibody.