CHP2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520, CHP2, HCA520, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O43745 | | Иммуноген | Synthesized peptide derived from internal of humanCHP2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.<br/><br/>Loftus B.J., Genomics 60:295-308(1999).<br/>Wang Y., J. Immunol. 169:1102-1109(2002).<br/>Pang T., J. Biol. Chem. 277:43771-43777(2002).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, K562 cells and HT-29 cells, using CHP2 antibody.
 | | | |
Информация для заказа |
Наименование: CHP2 Antibody.